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Jeen-Woo Park Selected Research

NADP (NADPH)

5/2018IDH2 Deficiency Aggravates Fructose-Induced NAFLD by Modulating Hepatic Fatty Acid Metabolism and Activating Inflammatory Signaling in Female Mice.
1/2018IDH2 deficiency increases the liver susceptibility to ischemia-reperfusion injury via increased mitochondrial oxidative injury.
4/2017Mitochondrial NADP+-Dependent Isocitrate Dehydrogenase Deficiency Exacerbates Mitochondrial and Cell Damage after Kidney Ischemia-Reperfusion Injury.
8/2014Mitochondrial NADP(+)-dependent isocitrate dehydrogenase knockdown inhibits tumorigenicity of melanoma cells.
4/2014Attenuated mitochondrial NADP+-dependent isocitrate dehydrogenase activity induces apoptosis and hypertrophy of H9c2 cardiomyocytes.
2/2014Suppression of tumorigenesis in mitochondrial NADP(+)-dependent isocitrate dehydrogenase knock-out mice.
4/2013Silencing of mitochondrial NADP(+)-dependent isocitrate dehydrogenase gene enhances glioma radiosensitivity.
8/2012RNA interference targeting cytosolic NADP(+)-dependent isocitrate dehydrogenase exerts anti-obesity effect in vitro and in vivo.
12/2010Modulation of hypoxia-inducible factor-1α expression by mitochondrial NADP+-dependent isocitrate dehydrogenase.
3/2009Role of cytosolic NADP+-dependent isocitrate dehydrogenase in ischemia-reperfusion injury in mouse kidney.
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Jeen-Woo Park Research Topics

Disease

24Neoplasms (Cancer)
01/2020 - 10/2007
10Mitochondrial Diseases (Mitochondrial Disease)
10/2019 - 09/2008
8Inflammation (Inflammations)
01/2020 - 05/2008
7Ischemia
01/2018 - 07/2006
6Reperfusion Injury
04/2017 - 07/2006
5Prostatic Neoplasms (Prostate Cancer)
03/2013 - 08/2010
4Melanoma (Melanoma, Malignant)
04/2019 - 08/2014
4Hypertrophy
01/2018 - 07/2012
4Fibrosis (Cirrhosis)
01/2016 - 12/2013
3Liver Failure
01/2020 - 01/2018
3Lung Injury
12/2018 - 01/2017
3Non-alcoholic Fatty Liver Disease
07/2018 - 01/2017
3Cardiovascular Diseases (Cardiovascular Disease)
07/2018 - 01/2017
3Parkinson Disease (Parkinson's Disease)
04/2015 - 03/2005
3Hyperglycemia
01/2008 - 12/2004
2Necrosis
01/2020 - 11/2006
2Alcoholic Liver Diseases (Alcoholic Liver Disease)
01/2020 - 01/2017
2Fatty Liver
01/2020 - 07/2018
2Macular Degeneration (Age-Related Maculopathy)
08/2019 - 12/2016
2Neoplasm Metastasis (Metastasis)
04/2019 - 02/2014
2Hypoxia (Hypoxemia)
03/2019 - 12/2010
2Carcinoma (Carcinomatosis)
02/2019 - 03/2013
2Lung Diseases (Lung Disease)
12/2018 - 01/2017
2Lewis Lung Carcinoma
12/2018 - 01/2017
2Neurodegenerative Diseases (Neurodegenerative Disease)
10/2018 - 10/2017
2Glioma (Gliomas)
10/2018 - 04/2013
2Metabolic Syndrome (Dysmetabolic Syndrome X)
05/2018 - 08/2012
2Cardiomegaly (Heart Hypertrophy)
01/2018 - 03/2015
2Obesity
10/2016 - 08/2012
2Ureteral Obstruction
01/2016 - 12/2013
2Carcinogenesis
02/2014 - 02/2012
2Colonic Neoplasms (Colon Cancer)
07/2012 - 04/2011
2Diabetes Complications
01/2008 - 06/2007
1Bone Resorption
12/2019
1Skin Neoplasms (Skin Cancer)
03/2019
1Congenital Abnormalities (Deformity)
02/2019
1Sensorineural Hearing Loss
01/2019
1Ototoxicity
01/2019
1Hearing Loss (Hearing Impairment)
01/2019
1Acute Liver Failure (Fulminant Hepatic Failure)
11/2018
1Wounds and Injuries (Trauma)
07/2018
1Metabolic Diseases (Metabolic Disease)
05/2018

Drug/Important Bio-Agent (IBA)

19Reactive Oxygen Species (Oxygen Radicals)IBA
10/2019 - 07/2012
13Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
10/2018 - 03/2002
13Small Interfering RNA (siRNA)IBA
01/2017 - 10/2007
11NADP (NADPH)IBA
05/2018 - 03/2002
9EnzymesIBA
01/2020 - 11/2006
9Proteins (Proteins, Gene)FDA Link
07/2018 - 08/2010
8AntioxidantsIBA
01/2019 - 11/2006
3Acetaminophen (Paracetamol)FDA LinkGeneric
01/2020 - 07/2018
3oxalomalic acidIBA
04/2019 - 12/2016
3salicylhydroxamic acid (SHAM)IBA
01/2018 - 01/2014
3Superoxides (Superoxide)IBA
07/2012 - 07/2006
3Glucose (Dextrose)FDA LinkGeneric
01/2008 - 12/2004
3Free RadicalsIBA
01/2008 - 12/2004
2Biomarkers (Surrogate Marker)IBA
12/2019 - 01/2017
2LipidsIBA
08/2019 - 08/2012
2Therapeutic UsesIBA
03/2019 - 01/2019
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2019 - 12/2016
2Pharmaceutical PreparationsIBA
03/2019 - 11/2018
2Acrolein (Aqualin)IBA
12/2018 - 01/2017
2PolyphenolsIBA
07/2018 - 04/2011
2FructoseIBA
05/2018 - 01/2018
2Phosphotransferases (Kinase)IBA
04/2017 - 02/2012
21- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
08/2016 - 05/2011
2Hydrogen Sulfide (Sulfide, Hydrogen)IBA
09/2015 - 12/2013
2CurcuminIBA
11/2013 - 04/2011
2Doxorubicin (Adriamycin)FDA LinkGeneric
03/2013 - 07/2012
2Ursolic AcidIBA
03/2013 - 02/2012
2TriterpenesIBA
03/2013 - 02/2012
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2013 - 10/2007
2StaurosporineIBA
03/2013 - 02/2009
2Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
07/2011 - 07/2006
2Immunoglobulin G (IgG)IBA
04/2009 - 03/2005
2Ethanol (Ethyl Alcohol)IBA
04/2009 - 09/2008
1MicroRNAs (MicroRNA)IBA
01/2020
1erastinIBA
01/2020
1pelargonidinIBA
01/2020
1morinIBA
08/2019
1Matrix Metalloproteinases (MMPs)IBA
04/2019
1MorpholinosIBA
02/2019
1AndrogensIBA
02/2019
1Biological ProductsIBA
02/2019
1mitoquinoneIBA
01/2019
1Glutathione (Reduced Glutathione)IBA
01/2019
1hesperetinIBA
12/2018
1Mitogen-Activated Protein KinasesIBA
11/2018
1antiarrhythmic peptide (AAP)IBA
11/2018
1Nitric Oxide (Nitrogen Monoxide)FDA Link
10/2018
1CytokinesIBA
10/2018
1FlavonoidsIBA
07/2018
1Silybin (Lagosa)IBA
07/2018
1Chlorogenic AcidIBA
07/2018
1Fatty Acids (Saturated Fatty Acids)IBA
05/2018
1CollagenIBA
04/2018
1naringinIBA
01/2018
1LipopolysaccharidesIBA
01/2018

Therapy/Procedure

6Therapeutics
04/2019 - 02/2008
3Radiotherapy
11/2013 - 03/2012
3Drug Therapy (Chemotherapy)
08/2010 - 10/2007